A 2017 Consumer Reports survey found that over 55% of Americans regularly take prescription medications — four, on average (Consumer Reports, 2017).
[M]ore than half of us are existing, daily, under the influence of polypharmacy; that is, simultaneously using multiple medications, day after day. . . .
[A] 2018 University of Chicago study was the first to demonstrate that simultaneous use of prescription medications is associated with a greater likelihood of experiencing depression.